Here's a quick example on how to use sodium_crypto_box(); where you have 2 people exchanging a $message, where person 1 encrypts it so that only person 2 can decrypt it, and be sure that person 1 actually sent it (without it being tampered with).
<?php
$keypair1 = sodium_crypto_box_keypair();
$keypair1_public = sodium_crypto_box_publickey($keypair1);
$keypair1_secret = sodium_crypto_box_secretkey($keypair1);
$keypair2 = sodium_crypto_box_keypair();
$keypair2_public = sodium_crypto_box_publickey($keypair2);
$keypair2_secret = sodium_crypto_box_secretkey($keypair2);
$message = 'hello';
$nonce = random_bytes(SODIUM_CRYPTO_BOX_NONCEBYTES);
$encryption_key = sodium_crypto_box_keypair_from_secretkey_and_publickey($keypair1_secret, $keypair2_public);
$encrypted = sodium_crypto_box($message, $nonce, $encryption_key);
echo base64_encode($encrypted) . "\n";
$decryption_key = sodium_crypto_box_keypair_from_secretkey_and_publickey($keypair2_secret, $keypair1_public);
$decrypted = sodium_crypto_box_open($encrypted, $nonce, $decryption_key);
echo $decrypted . "\n";
?>